Malaria is a leading cause of morbidity and mortality worldwide.
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Researchers reported new findings from their Phase 2b trial following the administration of a booster dose of the candidate malaria vaccine, R21/Matrix-M™
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In their findings, they found that a vaccine booster dose at one year following a primary three-dose regime maintained high efficacy against malaria.
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The findings offer hope that the vaccine, called R21, could be an effective weapon in the fight against malaria, which is one of the biggest killers globally.
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The co-inventor of a vaccine said he hopes it could be approved by as early as next year after the latest trial results were successful.
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Professor Adrian Hill, believes R21 could help to reduce deaths from the disease by 70% by 2030 and eradicate it by 2040.
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This double-blind phase 1/2b randomised controlled trial was done in children aged 5–17 months in Nanoro, Burkina Faso.
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he R21 vaccine has been tested in 450 children aged between 5 and 17 months in Burkina Faso, a country in which malaria infections are seasonal.
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This study published in The lancet infectious diseases