GenomicHub

What is Genome?

Why sequence a genome?

What are applications of Genomics?

What is genomic data?

Genomics data resources ?

Top GitHub repositories for Bioinformatics, Genomics and Data analysis


What is Genome?

An organism's complete set of DNA is called its genome. Virtually every single cell in the body contains a complete copy of the approximately 3 billion DNA base pairs, or letters, that make up the human genome.

Why sequence a genome?

Learning more about genomes can help us to identify the cause of genetic diseases. Some rare diseases are caused by as little as a single change (variant), like a spelling mistake, in someone’s DNA. Looking at the genome of a person affected by a rare disease can help find which DNA changes might be causing the problem.

In cancer, the tumour cells have developed a different genome to the healthy cells. Comparing the normal and cancer genomes may give clues about ways to treat the cancer. When the genome sequences of patients with the same condition are compared, it is possible to see patterns. These patterns can be put together with health information. Once this is done we may be able to link particular patterns with whether people are likely to become ill and, if so, how severe their illness is likely to be.

Application of Genomics

Genomics is becoming an important part of the healthcare agenda. Genome-based research is already enabling medical researchers to develop improved diagnostics, more effective therapeutic strategies, evidence-based approaches for demonstrating clinical efficacy, and better decision-making tools for patients and providers. Ultimately, it appears inevitable that treatments will be tailored to a patient's particular genomic makeup. Thus, the role of genetics in health care is starting to change profoundly and the first examples of the era of genomic medicine are upon us.


What is genomic data?

As biomedical research projects and large-scale collaborations grow rapidly, the amount of genomic data being generated is also increasing, with roughly 2 to 40 billion gigabytes of data now generated each year. Genomic data science is a field of study that enables researchers to use powerful computational and statistical methods to decode the functional information hidden in DNA sequence. Applied in the context of genomic medicine, these data science tools help researchers and clinicians uncover how differences in DNA affect human health and disease.


Genomics data sources:

Recently genomic sequence data have been produced in a exponential way. These data have also created new challenges related to storage, extract information and visualization. Here we will compile different sources of genomics data, analysis tools, and other resources.

update...soon...


Top GitHub repositories for Bioinformatics, Genomics and Data analysis

Seandavi (By Sean Davis)

This Github repository is very good resource for Single Cell RNAseq data analysis, about cancer variants database and information about NCI-GDC (TCGA) data sharing platform. seandavi (Sean Davis)

crazyhottommy (By Ming Tang)

An extensive resources for handling large-scale genomic data and pipelining workflows. Tutorials and pipelines for processing whole-exome, whole-genome DNAseq, RNAseq, single-cell RNAseq, ChIP-seq, and ATACseq data. crazyhottommy (Ming Tang)

kevinblighe (By Kevin Blighe)

Best repository for Bioinformatics and Genomics data analysis and visualization. Curated list of R and Bioconductor packages and data resources for multi-omics tools. Developer of widely used tools: EnhancedVolcano, RegParallel and PCAtools. kevinblighe (Kevin Blighe )

coming more....

 


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Here we will share some exciting startups and innovative ideas and stories related to Biomedicine and healthcare field.


Cambridge Innovation Capital plc and IP Group plc announce the creation of Wellcome Trust Sanger Institute spin-out company, Microbiotica:

Based on ground-breaking research at the Wellcome Trust Sanger Institute into the role of the human microbiome in disease. Goal is to create the world’s leading company focused on microbiome biology and its use in medicine. Cambridge Innovation Capital and IP Group co-lead £8m funding round. Click Here


Matchmaker, matchmaker, find me a grant

Recommendation engine Instrumentl aims to speed grant searching. See detail
Instrumentl:  Instrumentl matches scientists to the best grants for their research. Tell us about your project, and we'll let you know exactly which grants you're eligible for. No more Google searching or hunting through clunky databases. For more click here


Here we will share some exciting startups and innovative ideas and stories related to Biomedicine and healthcare field.


Cambridge Innovation Capital plc and IP Group plc announce the creation of Wellcome Trust Sanger Institute spin-out company, Microbiotica:

Based on ground-breaking research at the Wellcome Trust Sanger Institute into the role of the human microbiome in disease. Goal is to create the world’s leading company focused on microbiome biology and its use in medicine. Cambridge Innovation Capital and IP Group co-lead £8m funding round. Click Here


Matchmaker, matchmaker, find me a grant

Recommendation engine Instrumentl aims to speed grant searching. See detail
Instrumentl:  Instrumentl matches scientists to the best grants for their research. Tell us about your project, and we'll let you know exactly which grants you're eligible for. No more Google searching or hunting through clunky databases. For more click here