PhD scholarship

 PhD scholarship in Bioinformatics, Genomics and Life Science:


Update  on  June 18, 2018

PhD candidate in Bioinformatics

BioMedaqu project: Aquaculture meets Biomedicine: Innovation in Skeletal Health research (http://www.giga.uliege.be/biomedaqu). BioMedaqu is a Marie Sklodowska-Curie Innovative Training Network (MCSA-ITN) with the primary research aim to create an innovative expertise combining research in skeletal biology of aquaculture fish species with that in biomedical models and humans. In total, 15 Early Stage Researchers (ESRs) will be appointed by the BioMedaquconsortium for 36 months each.

The ideal candidate should have a Master in Computer Science orBiomedical Engineering, with a taste for deep/machine learning and modern software programming. The candidate will be supervised by senior scientific staff with a background in computer science (Prof. Wehenkel, Prof. Geurts, Dr. Raphaël Marée) in collaboration with biomedical researchers (Dr. Marc Muller) and other project partners.

Skills/Qualifications
The ideal candidate should have a Master in Computer Science or Biomedical Engineering, with a taste for deep/machine learning and modern software programming.

For detail click here


PhD in Molecular Biology/ Genetics

The IUF – Leibniz Research Institute for Environmental Medicine investigates the molecular mechanisms through which particles, radiation and environmental chemicals harm human health. The main working areas are environmentally induced aging of the cardiopulmonar system and the skin as well as disturbances of the nervous and immune system.

The project is focused on the potential of CRISPR/Cas9 in:
1) correcting genetic human diseases, susceptibilities toward environmental toxical;
2) generating mutations/SNP’s on different cell types in order to recapitulate human diseases/susceptibilities
3) identification of off-set targets.

Qualifications
We seek a highly motivated candidate (f/m) with a background in genetics and molecular biology. Expertise and interest in standard molecular biology techniques and cell culture is critical, and experience with plasmid cloning, gene editing and AAV vector production. The candidate is required to have strong skills in English and German and proven abilities to publish at a high international level with at least one first author publication.

For detail click here


Posted on June 15, 2018

PhD student in Prediction and Reprogramming of somatic cells

We invite applications for a PhD student position with a dual placement in the laboratory of Prof Antonio del Sol (https://wwwen.uni.lu/lcsb/research/computational_biology) at the Luxembourg Centre for Systems Biomedicine (Luxembourg) and at the laboratory of Professor Ernest Arenas (http://ernestarenaslab.org/) at the Karolinska Institute (Stockholm, Sweden).

The laboratory of Prof. Antonio del Sol is at the Luxembourg Centre for Systems Biomedicine, an interdisciplinary centre of the university of Luxembourg, which combines experimental and computational research to tackle a variety of biomedical problems. In particular, del Sol’s lab develops mathematical and computational approaches using multiple sources of biological information (e.g. transcriptomics, epigenomics, proteomics) in order to build computational models to analyse complex biological systems and disease processes from a systems biology perspective.

The successful student will develop a project aiming at reprogramming human fibroblasts or astrocytes into induced midbrain tissue and dopaminergic neurons in vitro based on single cell RNA-seq analysis and bioinformatics predictions.

APPLICATION DEADLINE 10/08/2018 12:00

For detail click here


PhD student positions at EPFL-Institute for Cancer Research

A PhD student position is available in the laboratory of Elisa Oricchio at EPFL-Institute for Experimental Cancer Research in Lausanne (Switzerland). Research in the lab focuses on the genetics of lymphoma and its translation into new therapies. We combine genomic analyses of human tumors with functional in vivo studies to assess the role of genetic lesions in lymphomagenesis, disease progression, and treatment response.

The ideal applicant should be interested in cancer biology and willing to learn molecular biology and cell culture techniques. Good programming skill and a background in bioinformatics will be preferred. In this position, you will join a dynamic team of cancer biologists and you will be able to work with high-throughput single cells analyses and high-throughput chromatin conformation capture data.

The candidate should send a motivation letter and the CV with the name of three referee to Dr. Oricchio: elisa.oricchio@epfl.ch

For detail click here


Posted on June 13, 2018

PhD Studentship - Metabolic reprogramming in human

PhD project title: Metabolic reprogramming in human ES/iPS cell models of neurodegenerative disease Supervisors: Lia Panman (MRC Toxicology Unit, University of Cambridge) Muireann Coen (AstraZeneca) Will Redfern (AstraZeneca) Project description The Medical Research Council Toxicology Unit, is an internationally renowned institution focussed on the delivery of field-changing mechanistic insights into toxicology and disease. The Unit is part of the University of Cambridge; it is currently located in Leicester and will be relocating to Cambridge in early 2020.

Students will be registered with the University of Cambridge for the duration of the studentship. Successful applicants will enjoy membership of a University of Cambridge College from commencement of their PhD in October 2018, but will initially have only limited access to College facilities due to the location of the Unit. The studentship if funded by the MRC Integrative-Toxicology Training Partnership (ITTP) and the training includes courses covering aspects of toxicology and molecular sciences. A part of the project will be carried out at AstraZeneca (Cambridge) and Imperial College (London) in collaboration with Muireann Coen and Will Redfern.

Candidates must expect to obtain qualifications at the level of a first-class or 2.1 Honours Degree in a biological science or related discipline and to fully satisfy the residence requirements of the UK Research Councils. A fees-only award will be available to EU nationals who are not ordinarily resident in the UK. Students who are liable for fees at the 'overseas' rate are not eligible for these studentships.

This advert will remain open until 30th June 2018 or until a suitable candidate is found.

For detail click here


PhD student position - Analyses of Chromatin Conformation Dynamics

The Regulatory Genomics Laboratory at the Max Planck Institute for Molecular Biomedicine in Muenster, Germany offers a PhD student position in Genomic Analyses of Chromatin Conformation Dynamics. The laboratory seeks to appoint a highly motivated scientist to work on dissecting the molecular mechanisms that regulate chromatin conformation in eukaryotes, which is a strong focus of the group.

We are looking for an enthusiastic and talented graduate (MSc or BSc) in biology, bioinformatics, or related fields, and with a strong drive to excel in a highly international and collaborative environment. Previous experience in genome-wide data analysis or programming skills (R, Python) will be advantageous, but not required prior to joining the laboratory. Please detail your interest or your previous experience in dealing with genomics data in the cover letter.

The position is offered initially as a fixed-term appointment for one year with the possibility of further extension following a successful evaluation. The position is available immediately. PhD students will receive a compensation according to pay level 13 (50 %) of the contracts for the civil service (TVöD, Tarifvertrag für den öffentlichen Dienst).

Applications received before 30 June 2018 will be considered first.

For detail click here


Posted on June, 2018

PhD student in "Computational population epigenomics"

The Institute of Computational Biology (Helmholtz Zentrum München) together with the Plant Science Department (Technical University of Munich, School of Life Sciences) is looking for a PhD student in "Computational population epigenomics“

The past decade has seen unprecedented advances in epigenomic measurement technologies. It is now possible to characterize epigenomes at high resolution and at reasonable cost. Efforts are underway in various species, including plants and humans, to measure the epigenomes of a large number of individuals with the goal of identifying functionally-relevant differences. A major bottleneck in these endeavors continues to be the need for efficient computational and bioinformatic methods that can aid in the genome-wide detection of patterns of epigenomic variation. The goal of the PhD is to develop and build on robust data analysis methods, and to device new metrics for the quantification of population epigenomic data.

Your Qualifications:

  • Appropriate studies (Masters/Diploma) in physics, mathematics, bioinformatics, computer science or related disciplines
  • Strong programming skills
  • Strong interest or ambition to learn about epigenetics and molecular biology
  • Good knowledge of statistics

For detail click here


Two PhD positions at the Department of Clinical Science

At the University of Bergen, Faculty of Medicine and Dentistry, Department of Clinical Science, two full-time temporary PhD-positions are available for a period of three (3) years.     The positions are part of the project “Dissecting causal mechanisms of non-coding variants in metabolic disease”, funded by the Norwegian Research Council.

The main objectives for the position are to experimentally manipulate candidate genetic variants, master regulators and target genes in human cells and animal models, and test effects of this manipulation on relevant cellular and organismal functions, and further link these effects to clinical data from patient cohort/prospective intervention studies. The work will be performed in a research environment with other doctoral and master students and researchers working on similar projects.

Qualifications and qualities

  • The successful applicant must hold a cand. med. or equivalent master’s degree, and should have experience from relevant research projects
  • Personal skills will be emphasized, including academic quality, research experience and ability to cooperate and work in a team. The candidate should be able to work independently, and have a strong commitment and enthusiasm for research and for learning/establishing new experimental/analytical techniques
  • The successful applicant must be fluent in oral and written English
  • The applicant must have a theoretical background in molecular and cell biology, genetics, metabolism and physiology, and should have prior knowledge of adipocyte biology

For detail click here


Posted on June, 2018

Ph.D. Student in Computational Biology and Machine Learning

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as in architecture, industrial management, urban planning, history and philosophy.

The project is concerned with Machine Learning and probabilistic modeling applied to single cell expression analysis. Methodologically, this project will be focused on advanced methods for computational inference such as Expectation Maximization, Dynamic Bayesian Models, and Deep Convolutional Neural Networks, as well as implementation of such methods on modern high performance computers and clusters. We expect to collaborate with groups developing new experimental methods, particularly single-cell methods, at SciLifeLab as well as with international collaborators.

Qualifications:
A suitable background for this position would be a master’s degree of Science in Computer Science, Statistics or any other discipline with large component of quantitative science. Programming skills and language skills are required. Knowledge of biology and computational biology are regarded as advantageous qualifications.

Last application date     15.May.2017

For more click here


PhD scholarship in Development of multiplex single molecule counting techniques

Applications are invited from suitably qualified candidates for a position funded by the Marie Sklodowska-Curie Innovative Training Network (MSCA-ITN) project “BBDiag” within the Horizon 2020 programme of the European Union. The appointment will be on a temporary basis for a maximum period of 3 years (PhD student) with start June or July 2017. The student will be employed as a PhD student at the Dept. Micro and Nanotechnology, Technical University of Denmark (DTU Nanotech.

Responsibilities and tasks
The PhD student will be a member of this multi-disciplinary team and will be responsible for the development of single molecule sensing techniques including

  • Micro-fabrication of clean room substrates for sample partitioning
  • Sandwich immunoassays
  • Multiplexing of assays
  • Testing clinical samples
  • Methods for statistical analysis

Qualifications
Candidates should have a master's degree in engineering (or a similar degree) with a background in nano-bio-technology, nanotechnology or molecular biology.

For more click here


Posted on March 22, 2017

PhD studentships in Biological Sciences

ESR (Early Stage Researcher) position for 36 months at Medical Research Council Cancer Unit, University of Cambridge, Cambridge, UK

The Frezza laboratory focuses on understanding the role of the mitochondrial enzyme and component of the tricarboxylic acid (TCA) cycle Fumarate Hydratase in tumorigenesis. We have recently demonstrated that fumarate, accumulated in FH-deficient cells, elicits a powerful epigenetic reprogramming that leads to the suppression of miRNA200, and induction of epithelial¿to-mesenchymal transition (Sciacovelli et al, Nature 2016). This epigenetic and phenotypic switch makes FH-deficient cells more motile and invasive, predisposing to metastasis. Although we demonstrated that fumarate has a role as epigenetic modifier, its effects on chromatin structure and function are still unknown. This project will help to elucidate the link between TCA cycle dysfunction, accumulation of fumarate, and downstream epigenetic changes involved in tumorigenesis. To this aim the ESR will investigate the hypothesis that fumarate controls the activity of histone and DNA demethylases involved in DNA and histone methylation, causing broad epigenetic changes. The ESR will first generate a 3D cellular model of FH-deficiency by deleting FH in human renal cell lines obtained using CRISPR technology.

PhD program starting date: 01/10/2017

Required Educational Level  Degree: Applicants should hold a Masters level Degree in Biological Sciences in the field of Biochemistry, Cell Biology, Cancer Biology.

The closing date for applications is 30th April 17. The date of interviews is TBC.

For detail click here


PhD position (Doctoral Researcher)  in Systems Biology

The Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute – (HKI, www.leibniz-hki.de) investigates the pathobiology of human-pathogenic fungi and identifies targets for the development of novel natural product-based antibiotics. The Research Group Systems Biology and Bioinformatics invites talented and highly gifted candidates to apply for a doctoral researcher.

The project is part of an international collaboration with Queen Mary Hospital, the flagship teaching hospital of The University of Hong Kong (Hong Kong). Our group has previously developed in house pipelines for the independent analysis of metagenomic, metatranscriptomic and meta-metabolomic data. In the framework of this project these pipelines will be further revised and upgraded to accommodate combined analysis for a large number of multi-meta-omic samples. Furthermore, we plan to integrate in novel ways these meta-omic datasets for modelling the association of microbial communities and C. albicans.

Your profile: A strong interest in conducting collaborative research on the topic outlined above is paramount. Candidates are expected to be interested in working at the boundaries of several research domains.

  • Master´s degree in Systems Biology, Computational Biology, Bioinformatics, Biophysics or a related discipline.
  • Knowledge in statistical methods in the context of biological systems.
  • Experience with programming (Python, Perl, C++, R).

Complete applications in English should include CV, certificates, transcripts, a brief statement of research experiences and interests and the addresses of two possible referees, and should be submitted by April 21, 2017 via the online application system of the HKI.

For detail click here


Posted on March 10, 2017

PhD studentship in Biomedicine

Project: Investigation into the impact and effect of systemic iron deficiency, and iron repletion, on skeletal muscle function

 The work will involve the mechanistic role of iron and its function in tissues. Iron has two important functions: assisting in the manufacture of blood cells to transport oxygen, as well as providing key ingredients in the cellular ‘power house’ (mitochondria) that uses oxygen to generate energy for muscles. New intravenous (IV) iron treatments are available, enabling full treatment in a single infusion. IV iron is known to be efficacious for correcting iron deficiency with or without anaemia, but we do not know if overall fitness and skeletal muscle function is improved. Furthermore, we do not know the mechanism of how ID, anaemia or treatments thereof may impact iron repletion on tissues.

Person Specification

•A good (First or Upper Second Class Bachelor’s) degree in a biomedical or pharmacological subjects (or equivalent EU/overseas degree), and ideally an MSc in a related area.

•An interest in iron deficiency, anaemia and mitochondrial biochemistry, and a desire to learn more.

•Strong analytical/statistical skills.

•Enthusiastic, organised with good communication skills - especially in written English.

•A strong work ethic, with the ability to think creatively and work independently.

•Develop pre-clinical models of iron deficiency and anaemia under the direction of Professor Toby Richards and Dr Anna Butcher.

For detail click here


E-cigaratte use in pregnancy and diabetes PhD scholarship

One in four Australian adults has either type 2 diabetes or impaired glucose tolerance. Cigarette smoking increases the risk of diabetes. E-cigarettes are seen as the new safe alternative to tobacco cigarettes, but our preliminary studies would suggest otherwise. This PhD project (in collaboration with A/Prof Brian Oliver) will evaluate the risks posed by maternal vaping upon the development of diabetes in model systems. The results will inform the community of the risks that e-cigarette use has, and ultimately reduce the morbidity and mortality of diabetes.

Essential qualifications 
H1 Honours or equivalent (H2 Honours with 1 year post qualification research experience / Research Masters).

How to apply
Open only to Australian Residents or Citizens for commencement anytime between March - August 2017.  Applicants are encouraged to phone Dr Hui Chen on 9514 1328 prior to applying. Send your CV and a half page expression of interest to: Dr Hui Chen.

For detail click here


Posted on March 07, 2017

Epigenetics of chlamydial infection PhD scholarship

Chlamydial infections and their associated diseases are often asymptomatic and severe disease outcomes can take years to manifest. This project will apply bioinformatic analysis of high-throughput sequencing data to gain insights into fundamental chlamydial biology and disease pathogenesis by epigenetic dysregulation of the human genome. Epigenetically dysregulated genes may facilitate chlamydial pathogenesis and disease progression, either by direct chlamydial interference or by innate responses, and may be candidate biomarkers of infection or disease.
Desirable skills and qualifications
  • Expertise in programming (R, Python or similar), data visualisation and/or computational biology;
  • Open to international and domestic students for commencement in 2017.

How to apply

Send your CV and a half page expression of interest to: Associate Professor Garry Myers.
Applicants for the scholarship must also apply to be admitted to the PhD degree at UTS.
Applications close: 15 March 2017

For detail click here


PhD Position  Biomedical Image Analysis 

Location: Biomedical Comput er Vision Group  University of Heidelberg, BioQuant Center, IPMB, and DKFZ

The research group Biomedical Computer Vision (BMCV) at the University of Heidelberg and  the DKFZ currently offers a PhD position in the field of Biomedical Image Analysis. The task  is the development of innovative methods for  automated analysis of 3D microscopy images.  Focus  is  on  the  segmentation  and  quantification  of  cells  and  subcellular  structures  in  3D   volume images with the aim is to improv e medical diagnosis and therapy. The work is funded  by  the  Federal  Ministry  of  Education  and  Research  (BMBF)  and  carried  out  in  close   cooperation  with  biomedical  partners  at  Heidelberg  University  Hospital  and  the  DKFZ   Heidelberg.

Candidates   must   have   a   Master’s   (Diploma)   degree   in   Computer   Science,   Electrical    Engineering,    Medical    Informatics,    Biomedica l    Engineering,    Bioinformatics,    Applied     Mathematics,  Physics,  or  a  related  discipli ne.  We  expect  experience  in  Image  Analysis  as   well as good mathematical and programming skills. Candidates should be highly motivated,  team-minded, and interested in interdisciplinary research.

For detail click here


Posted on March 06, 2017

CRUK 4 Year PhD Studentships 2017

Studentships are fully funded for 4 years commencing October 2017. Cancer Research UK sponsorship includes generous stipend, tuition and bench fees. Students trained within our research groups will matriculate from the University of Manchester.

Tumour Suppressor Group - p53 Mutations in Small Cell Lung Cancer     
Applications Close Monday 10 April 2017 (2400 hrs GMT)     Interviews: Friday 21 April 2017

Applications are invited from exceptionally high calibre students – recent graduates or final year undergraduates who have, or are expected to obtain a first or upper second class honours degree and who are highly committed to pursuing a PhD in cancer research.  The importance of p53 mutations in human cancer is clear with over 50% frequency across all cancers but reaching more than 90% in small cell lung cancer.  This research is looking into the p53 mutations and patient response to chemotherapy in small cell lung cancer.  Informal enquiries should be addressed to Dr Patricia Muller - pgt@cruk.manchester.ac.uk

RNA and Computational Biology Group - Applying High Performance Computing to the Cancer Genome   
Applications Close Thursday 13 April 2017 (2400 hrs GMT)     Interviews: Friday 28 April 2017

Applications are invited from exceptionally high calibre students – recent graduates or final year undergraduates who have, or are expected to obtain a first or upper second class honours degree and who are highly committed to pursuing a PhD in cancer research.  While a background in biology is useful, the project is computational in nature and excellent scientists from a computational background who are keen to develop a better understanding of cancer are encouraged to apply.  Informal enquiries should be addressed to Dr Crispin Miller - crispin.miller@cruk.manchester.ac.uk

For detail click here


20 ICFO International PhD Fellowship positions

ICFO is offering up to 20 PhD positions to well-qualified graduate students, who wish to obtain a doctoral degree in any of the research fields covered at ICFO. Research is carried out at ICFO.

Our PhD-program brings together top-level training and teaching for young scientists, benefiting from the extensive course offerings of local universities and focused instruction by ICFO professors, in a stimulating, international and interdisciplinary environment. PhD-students have the opportunity to take advantage of our network of excellence, consisting in partners of national and international research institutes and universities, as well as industrial partners in the field.

Our International PhD Fellowship Program welcomes applications from individuals with a degree in a field of science and engineering related to the ICFO research activities.  Fellowships will be offered across all ICFO research groups in the following research areas:

  • Biophysics & Biomedical Optics
  • Optical Sensing, Optoelectronics & Photovoltaics
  • Nonlinear Optics, Ultrafast Optics & Atto-Physics
  • Nanophotonics, Optomechanics & Nanomechanics
  • Experimental Quantum Optics & Quantum Information
  • Theoretical Nanophotonics, Quantum Optics & Quantum Information

application deadline: 26th of March, 2017

For detail click here

 PhD scholarship in Bioinformatics, Genomics and Life Science:


Update  on  June 13, 2018

PhD Studentship - Metabolic reprogramming in human

PhD project title: Metabolic reprogramming in human ES/iPS cell models of neurodegenerative disease Supervisors: Lia Panman (MRC Toxicology Unit, University of Cambridge) Muireann Coen (AstraZeneca) Will Redfern (AstraZeneca) Project description The Medical Research Council Toxicology Unit, is an internationally renowned institution focussed on the delivery of field-changing mechanistic insights into toxicology and disease. The Unit is part of the University of Cambridge; it is currently located in Leicester and will be relocating to Cambridge in early 2020.

Students will be registered with the University of Cambridge for the duration of the studentship. Successful applicants will enjoy membership of a University of Cambridge College from commencement of their PhD in October 2018, but will initially have only limited access to College facilities due to the location of the Unit. The studentship if funded by the MRC Integrative-Toxicology Training Partnership (ITTP) and the training includes courses covering aspects of toxicology and molecular sciences. A part of the project will be carried out at AstraZeneca (Cambridge) and Imperial College (London) in collaboration with Muireann Coen and Will Redfern.

Candidates must expect to obtain qualifications at the level of a first-class or 2.1 Honours Degree in a biological science or related discipline and to fully satisfy the residence requirements of the UK Research Councils. A fees-only award will be available to EU nationals who are not ordinarily resident in the UK. Students who are liable for fees at the 'overseas' rate are not eligible for these studentships.

This advert will remain open until 30th June 2018 or until a suitable candidate is found.

For detail click here


PhD student position - Analyses of Chromatin Conformation Dynamics

The Regulatory Genomics Laboratory at the Max Planck Institute for Molecular Biomedicine in Muenster, Germany offers a PhD student position in Genomic Analyses of Chromatin Conformation Dynamics. The laboratory seeks to appoint a highly motivated scientist to work on dissecting the molecular mechanisms that regulate chromatin conformation in eukaryotes, which is a strong focus of the group.

We are looking for an enthusiastic and talented graduate (MSc or BSc) in biology, bioinformatics, or related fields, and with a strong drive to excel in a highly international and collaborative environment. Previous experience in genome-wide data analysis or programming skills (R, Python) will be advantageous, but not required prior to joining the laboratory. Please detail your interest or your previous experience in dealing with genomics data in the cover letter.

The position is offered initially as a fixed-term appointment for one year with the possibility of further extension following a successful evaluation. The position is available immediately. PhD students will receive a compensation according to pay level 13 (50 %) of the contracts for the civil service (TVöD, Tarifvertrag für den öffentlichen Dienst).

Applications received before 30 June 2018 will be considered first.

For detail click here


Posted on June, 2018

PhD student in "Computational population epigenomics"

The Institute of Computational Biology (Helmholtz Zentrum München) together with the Plant Science Department (Technical University of Munich, School of Life Sciences) is looking for a PhD student in "Computational population epigenomics“

The past decade has seen unprecedented advances in epigenomic measurement technologies. It is now possible to characterize epigenomes at high resolution and at reasonable cost. Efforts are underway in various species, including plants and humans, to measure the epigenomes of a large number of individuals with the goal of identifying functionally-relevant differences. A major bottleneck in these endeavors continues to be the need for efficient computational and bioinformatic methods that can aid in the genome-wide detection of patterns of epigenomic variation. The goal of the PhD is to develop and build on robust data analysis methods, and to device new metrics for the quantification of population epigenomic data.

Your Qualifications:

  • Appropriate studies (Masters/Diploma) in physics, mathematics, bioinformatics, computer science or related disciplines
  • Strong programming skills
  • Strong interest or ambition to learn about epigenetics and molecular biology
  • Good knowledge of statistics

For detail click here


Two PhD positions at the Department of Clinical Science

At the University of Bergen, Faculty of Medicine and Dentistry, Department of Clinical Science, two full-time temporary PhD-positions are available for a period of three (3) years.     The positions are part of the project “Dissecting causal mechanisms of non-coding variants in metabolic disease”, funded by the Norwegian Research Council.

The main objectives for the position are to experimentally manipulate candidate genetic variants, master regulators and target genes in human cells and animal models, and test effects of this manipulation on relevant cellular and organismal functions, and further link these effects to clinical data from patient cohort/prospective intervention studies. The work will be performed in a research environment with other doctoral and master students and researchers working on similar projects.

Qualifications and qualities

  • The successful applicant must hold a cand. med. or equivalent master’s degree, and should have experience from relevant research projects
  • Personal skills will be emphasized, including academic quality, research experience and ability to cooperate and work in a team. The candidate should be able to work independently, and have a strong commitment and enthusiasm for research and for learning/establishing new experimental/analytical techniques
  • The successful applicant must be fluent in oral and written English
  • The applicant must have a theoretical background in molecular and cell biology, genetics, metabolism and physiology, and should have prior knowledge of adipocyte biology

For detail click here


Posted on June, 2018

Ph.D. Student in Computational Biology and Machine Learning

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as in architecture, industrial management, urban planning, history and philosophy.

The project is concerned with Machine Learning and probabilistic modeling applied to single cell expression analysis. Methodologically, this project will be focused on advanced methods for computational inference such as Expectation Maximization, Dynamic Bayesian Models, and Deep Convolutional Neural Networks, as well as implementation of such methods on modern high performance computers and clusters. We expect to collaborate with groups developing new experimental methods, particularly single-cell methods, at SciLifeLab as well as with international collaborators.

Qualifications:
A suitable background for this position would be a master’s degree of Science in Computer Science, Statistics or any other discipline with large component of quantitative science. Programming skills and language skills are required. Knowledge of biology and computational biology are regarded as advantageous qualifications.

Last application date     15.May.2017

For more click here


PhD scholarship in Development of multiplex single molecule counting techniques

Applications are invited from suitably qualified candidates for a position funded by the Marie Sklodowska-Curie Innovative Training Network (MSCA-ITN) project “BBDiag” within the Horizon 2020 programme of the European Union. The appointment will be on a temporary basis for a maximum period of 3 years (PhD student) with start June or July 2017. The student will be employed as a PhD student at the Dept. Micro and Nanotechnology, Technical University of Denmark (DTU Nanotech.

Responsibilities and tasks
The PhD student will be a member of this multi-disciplinary team and will be responsible for the development of single molecule sensing techniques including

  • Micro-fabrication of clean room substrates for sample partitioning
  • Sandwich immunoassays
  • Multiplexing of assays
  • Testing clinical samples
  • Methods for statistical analysis

Qualifications
Candidates should have a master's degree in engineering (or a similar degree) with a background in nano-bio-technology, nanotechnology or molecular biology.

For more click here


Posted on March 22, 2017

PhD studentships in Biological Sciences

ESR (Early Stage Researcher) position for 36 months at Medical Research Council Cancer Unit, University of Cambridge, Cambridge, UK

The Frezza laboratory focuses on understanding the role of the mitochondrial enzyme and component of the tricarboxylic acid (TCA) cycle Fumarate Hydratase in tumorigenesis. We have recently demonstrated that fumarate, accumulated in FH-deficient cells, elicits a powerful epigenetic reprogramming that leads to the suppression of miRNA200, and induction of epithelial¿to-mesenchymal transition (Sciacovelli et al, Nature 2016). This epigenetic and phenotypic switch makes FH-deficient cells more motile and invasive, predisposing to metastasis. Although we demonstrated that fumarate has a role as epigenetic modifier, its effects on chromatin structure and function are still unknown. This project will help to elucidate the link between TCA cycle dysfunction, accumulation of fumarate, and downstream epigenetic changes involved in tumorigenesis. To this aim the ESR will investigate the hypothesis that fumarate controls the activity of histone and DNA demethylases involved in DNA and histone methylation, causing broad epigenetic changes. The ESR will first generate a 3D cellular model of FH-deficiency by deleting FH in human renal cell lines obtained using CRISPR technology.

PhD program starting date: 01/10/2017

Required Educational Level  Degree: Applicants should hold a Masters level Degree in Biological Sciences in the field of Biochemistry, Cell Biology, Cancer Biology.

The closing date for applications is 30th April 17. The date of interviews is TBC.

For detail click here


PhD position (Doctoral Researcher)  in Systems Biology

The Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute – (HKI, www.leibniz-hki.de) investigates the pathobiology of human-pathogenic fungi and identifies targets for the development of novel natural product-based antibiotics. The Research Group Systems Biology and Bioinformatics invites talented and highly gifted candidates to apply for a doctoral researcher.

The project is part of an international collaboration with Queen Mary Hospital, the flagship teaching hospital of The University of Hong Kong (Hong Kong). Our group has previously developed in house pipelines for the independent analysis of metagenomic, metatranscriptomic and meta-metabolomic data. In the framework of this project these pipelines will be further revised and upgraded to accommodate combined analysis for a large number of multi-meta-omic samples. Furthermore, we plan to integrate in novel ways these meta-omic datasets for modelling the association of microbial communities and C. albicans.

Your profile: A strong interest in conducting collaborative research on the topic outlined above is paramount. Candidates are expected to be interested in working at the boundaries of several research domains.

  • Master´s degree in Systems Biology, Computational Biology, Bioinformatics, Biophysics or a related discipline.
  • Knowledge in statistical methods in the context of biological systems.
  • Experience with programming (Python, Perl, C++, R).

Complete applications in English should include CV, certificates, transcripts, a brief statement of research experiences and interests and the addresses of two possible referees, and should be submitted by April 21, 2017 via the online application system of the HKI.

For detail click here


Posted on March 10, 2017

PhD studentship in Biomedicine

Project: Investigation into the impact and effect of systemic iron deficiency, and iron repletion, on skeletal muscle function

 The work will involve the mechanistic role of iron and its function in tissues. Iron has two important functions: assisting in the manufacture of blood cells to transport oxygen, as well as providing key ingredients in the cellular ‘power house’ (mitochondria) that uses oxygen to generate energy for muscles. New intravenous (IV) iron treatments are available, enabling full treatment in a single infusion. IV iron is known to be efficacious for correcting iron deficiency with or without anaemia, but we do not know if overall fitness and skeletal muscle function is improved. Furthermore, we do not know the mechanism of how ID, anaemia or treatments thereof may impact iron repletion on tissues.

Person Specification

•A good (First or Upper Second Class Bachelor’s) degree in a biomedical or pharmacological subjects (or equivalent EU/overseas degree), and ideally an MSc in a related area.

•An interest in iron deficiency, anaemia and mitochondrial biochemistry, and a desire to learn more.

•Strong analytical/statistical skills.

•Enthusiastic, organised with good communication skills - especially in written English.

•A strong work ethic, with the ability to think creatively and work independently.

•Develop pre-clinical models of iron deficiency and anaemia under the direction of Professor Toby Richards and Dr Anna Butcher.

For detail click here


E-cigaratte use in pregnancy and diabetes PhD scholarship

One in four Australian adults has either type 2 diabetes or impaired glucose tolerance. Cigarette smoking increases the risk of diabetes. E-cigarettes are seen as the new safe alternative to tobacco cigarettes, but our preliminary studies would suggest otherwise. This PhD project (in collaboration with A/Prof Brian Oliver) will evaluate the risks posed by maternal vaping upon the development of diabetes in model systems. The results will inform the community of the risks that e-cigarette use has, and ultimately reduce the morbidity and mortality of diabetes.

Essential qualifications 
H1 Honours or equivalent (H2 Honours with 1 year post qualification research experience / Research Masters).

How to apply
Open only to Australian Residents or Citizens for commencement anytime between March - August 2017.  Applicants are encouraged to phone Dr Hui Chen on 9514 1328 prior to applying. Send your CV and a half page expression of interest to: Dr Hui Chen.

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Posted on March 07, 2017

Epigenetics of chlamydial infection PhD scholarship

Chlamydial infections and their associated diseases are often asymptomatic and severe disease outcomes can take years to manifest. This project will apply bioinformatic analysis of high-throughput sequencing data to gain insights into fundamental chlamydial biology and disease pathogenesis by epigenetic dysregulation of the human genome. Epigenetically dysregulated genes may facilitate chlamydial pathogenesis and disease progression, either by direct chlamydial interference or by innate responses, and may be candidate biomarkers of infection or disease.
Desirable skills and qualifications
  • Expertise in programming (R, Python or similar), data visualisation and/or computational biology;
  • Open to international and domestic students for commencement in 2017.

How to apply

Send your CV and a half page expression of interest to: Associate Professor Garry Myers.
Applicants for the scholarship must also apply to be admitted to the PhD degree at UTS.
Applications close: 15 March 2017

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PhD Position  Biomedical Image Analysis 

Location: Biomedical Comput er Vision Group  University of Heidelberg, BioQuant Center, IPMB, and DKFZ

The research group Biomedical Computer Vision (BMCV) at the University of Heidelberg and  the DKFZ currently offers a PhD position in the field of Biomedical Image Analysis. The task  is the development of innovative methods for  automated analysis of 3D microscopy images.  Focus  is  on  the  segmentation  and  quantification  of  cells  and  subcellular  structures  in  3D   volume images with the aim is to improv e medical diagnosis and therapy. The work is funded  by  the  Federal  Ministry  of  Education  and  Research  (BMBF)  and  carried  out  in  close   cooperation  with  biomedical  partners  at  Heidelberg  University  Hospital  and  the  DKFZ   Heidelberg.

Candidates   must   have   a   Master’s   (Diploma)   degree   in   Computer   Science,   Electrical    Engineering,    Medical    Informatics,    Biomedica l    Engineering,    Bioinformatics,    Applied     Mathematics,  Physics,  or  a  related  discipli ne.  We  expect  experience  in  Image  Analysis  as   well as good mathematical and programming skills. Candidates should be highly motivated,  team-minded, and interested in interdisciplinary research.

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Posted on March 06, 2017

CRUK 4 Year PhD Studentships 2017

Studentships are fully funded for 4 years commencing October 2017. Cancer Research UK sponsorship includes generous stipend, tuition and bench fees. Students trained within our research groups will matriculate from the University of Manchester.

Tumour Suppressor Group - p53 Mutations in Small Cell Lung Cancer     
Applications Close Monday 10 April 2017 (2400 hrs GMT)     Interviews: Friday 21 April 2017

Applications are invited from exceptionally high calibre students – recent graduates or final year undergraduates who have, or are expected to obtain a first or upper second class honours degree and who are highly committed to pursuing a PhD in cancer research.  The importance of p53 mutations in human cancer is clear with over 50% frequency across all cancers but reaching more than 90% in small cell lung cancer.  This research is looking into the p53 mutations and patient response to chemotherapy in small cell lung cancer.  Informal enquiries should be addressed to Dr Patricia Muller - pgt@cruk.manchester.ac.uk

RNA and Computational Biology Group - Applying High Performance Computing to the Cancer Genome   
Applications Close Thursday 13 April 2017 (2400 hrs GMT)     Interviews: Friday 28 April 2017

Applications are invited from exceptionally high calibre students – recent graduates or final year undergraduates who have, or are expected to obtain a first or upper second class honours degree and who are highly committed to pursuing a PhD in cancer research.  While a background in biology is useful, the project is computational in nature and excellent scientists from a computational background who are keen to develop a better understanding of cancer are encouraged to apply.  Informal enquiries should be addressed to Dr Crispin Miller - crispin.miller@cruk.manchester.ac.uk

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20 ICFO International PhD Fellowship positions

ICFO is offering up to 20 PhD positions to well-qualified graduate students, who wish to obtain a doctoral degree in any of the research fields covered at ICFO. Research is carried out at ICFO.

Our PhD-program brings together top-level training and teaching for young scientists, benefiting from the extensive course offerings of local universities and focused instruction by ICFO professors, in a stimulating, international and interdisciplinary environment. PhD-students have the opportunity to take advantage of our network of excellence, consisting in partners of national and international research institutes and universities, as well as industrial partners in the field.

Our International PhD Fellowship Program welcomes applications from individuals with a degree in a field of science and engineering related to the ICFO research activities.  Fellowships will be offered across all ICFO research groups in the following research areas:

  • Biophysics & Biomedical Optics
  • Optical Sensing, Optoelectronics & Photovoltaics
  • Nonlinear Optics, Ultrafast Optics & Atto-Physics
  • Nanophotonics, Optomechanics & Nanomechanics
  • Experimental Quantum Optics & Quantum Information
  • Theoretical Nanophotonics, Quantum Optics & Quantum Information

application deadline: 26th of March, 2017

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